Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721500 | 0.79 | THRB (0.53) | ALDH1A1LMNARECQLSRCCYP2D6 | |
| SCHEMBL19707707 | 0.78 | LMNA (0.56) | ALDH1A1LMNARECQLSRCCYP2D6 | |
| SCHEMBL241642 | 0.76 | CES2 (0.57) | ALDH1A1LMNARECQLSRCCYP2D6 | |
| SCHEMBL12861460 | 0.76 | DPP4 (0.45) | ALDH1A1LMNACCNA2CDK2CCNA1 | |
| SCHEMBL70230 | 0.76 | DPP4 (0.45) | ALDH1A1LMNACCNA2CDK2CCNA1 | |
| SCHEMBL12861930 | 0.76 | FAAH (0.57) | ALDH1A1LMNACCNA2CDK2CCNA1 | |
| SCHEMBL3761182 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNARECQLSRCCYP2D6 | |
| SCHEMBL70407 | 0.76 | FAAH (0.57) | ALDH1A1LMNACCNA2CDK2CCNA1 | |
| SCHEMBL8007655 | 0.76 | SRC (0.61) | ALDH1A1LMNARECQLSRCCYP2D6 | |
| SCHEMBL241909 | 0.73 | SRC (0.56) | LMNASRCCYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694251-B | A kind of new process preparing prasugrel hydrochloride | 南京简成医药科技有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-102395591-B | Method for preparing prasugrel | ZHEJIANG HUAHAI PHARM CO LTD | 2014-04-30 | — | — | CN | claimed |
| CN-103694251-A | Novel preparation process of prasugrel hydrochloride | NANJING JIANCHENG MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-102395591-A | Method for preparing prasugrel | ZHEJIANG HUAHAI PHARM CO LTD | 2012-03-28 | — | — | CN | claimed |
| CN-101993447-A | Method for synthesizing Prasugrel artificially | ZHEJIANG HUAHAI PHARM CO LTD | 2011-03-30 | — | — | CN | claimed |
| CN-104341433-B | A kind of preparation method of prasugrel intermediate | 鲁南制药集团股份有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-102558216-B | The preparation method of prasugrel | SHANGHAI SINE PHARMACEUTICAL CO., LTD. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-104341433-A | Preparation method of Prasugrel intermediate | LUNAN PHARM GROUP CORP | 2015-02-11 | — | — | CN | disclosed |
| CN-102241572-B | Preparation method and application of aromatic cyclopropyl butanone compound | ZHEJIANG JIUZHOU PHARM CO LTD | 2014-07-16 | — | — | CN | disclosed |
| CN-102395591-B | Method for preparing prasugrel | ZHEJIANG HUAHAI PHARM CO LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-103694251-A | Novel preparation process of prasugrel hydrochloride | NANJING JIANCHENG MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-102241612-B | Synthetic method of compound 2-cyclopropyl-1-(2-fluorophenyl)-2-carbonyl ethyl p-methylbenzensulfonate | UNIV NORTHWEST NORMAL | 2013-08-21 | — | — | CN | disclosed |
| CN-101250193-B | Method for preparing 2-methoxy-5-(alpha-cyclopropyl carbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothiophene [3,2-c] pyridine | SHANGHAI INST PHARM INDUSTRY | 2010-09-08 | — | — | CN | disclosed |
| CN-101250192-B | Method for preparing 5-(alpha-cyclopropyl carbonyl-2-fluorobenzyl)-2-oxo-2,4,5,6,7,7a-hexahydrothiophene [3,2-c] pyridine | SHANGHAI INST PHARM INDUSTRY | 2010-08-11 | — | — | CN | disclosed |
| CN-101735240-A | New preparation method for hexahydrothieno [3, 2-c] pyridine derivatives | SHANGHAI UTOPHARM CO LTD | 2010-06-16 | — | — | CN | disclosed |
| CN-101289454-A | Method for preparing 2-oxygen-2,4,5,6,7,7alpha-hexahydro thieno [3,2-c]pyridine | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-10-22 | — | — | CN | disclosed |
| CN-101250193-A | Method for preparing 2-methoxy-5-(alpha-cyclopropyl carbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothiophene [3,2-c] pyridine | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101250192-A | Method for preparing 5-(alpha-cyclopropyl carbonyl-2-fluorobenzyl)-2-oxo-2,4,5,6,7,7a-hexahydrothiophene [3,2-c] pyridine | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101245073-A | Medicine midbody and preparation method thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-101245072-A | Midbody for producing prasugrel and producing method thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-08-20 | — | — | CN | disclosed |