Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721500 | 0.79 | THRB (0.53) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL19707707 | 0.78 | LMNA (0.56) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL12861460 | 0.76 | DPP4 (0.45) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL12861930 | 0.76 | FAAH (0.57) | ALDH1A1LMNARECQLKMT2A | |
| SCHEMBL70230 | 0.76 | DPP4 (0.45) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL241642 | 0.76 | CES2 (0.57) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL70407 | 0.76 | FAAH (0.57) | ALDH1A1LMNARECQLKMT2A | |
| SCHEMBL27735697 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL8007655 | 0.76 | SRC (0.61) | ALDH1A1LMNARECQLCYP2D6SRC | |
| SCHEMBL986052 | 0.76 | CYP2D6 (0.37) | ALDH1A1LMNACYP2D6SRCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231575-A2 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Müködö Részvénytársaság (HU) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009068923-A2 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATES | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MŰKÖDŐ RÉSZVÉNYTÁRSASÁG (HU) | 2009-06-04 | — | — | WO | disclosed |