SCHEMBL27736772

SCHEMBL27736772

CO[Si](OC)(OC)c1ccc(CN)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.44
LOXL2 Q9Y4K0 7/20 0.44
MAOB P27338 2/20 0.41
ABAT P80404 1/20 0.41
ST14 Q9Y5Y6 1/20 0.40
LOX P28300 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
PSIP1 O75475 1/20 0.38
ADRB2 P07550 1/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
TPSAB1 Q15661 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37363 0.83 TAAR1 (0.55) LOXL2MAOBTAAR1
SCHEMBL27951580 0.82 LOXL2 (0.35) HRH3LOXL2MAOBABATST14
SCHEMBL20584032 0.81 LTA4H (0.41)
SCHEMBL50828 0.80 KDM4E (0.32)
SCHEMBL27608831 0.79 LOXL2 (0.46) LOXL2MAOBST14LOXTAAR1
SCHEMBL3098802 0.79 TP53 (0.40) TAAR1
SCHEMBL28245960 0.78 LOXL2 (0.41) HRH3LOXL2MAOBABATST14
SCHEMBL1225261 0.78 TAAR1 (0.36) HRH3MAOBTAAR1
SCHEMBL27593486 0.78 HRH3 (0.41) HRH3LOXL2MAOBABATST14
SCHEMBL2954747 0.77 TRPA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118122373-A Catalyst, preparation method thereof and application of catalyst in preparation of 2-aminopropanol by catalyzing acetol 中国科学院大连化学物理研究所 2024-06-04 CN claimed
CN-103910590-B A kind of biaryl compounds and preparation method thereof SHAOXING UNIVERSITY (CN) 2015-12-02 CN claimed
CN-103172479-B Preparation method for biaryl through palladium catalysis SHAOXING UNIVERSITY (CN) 2014-10-29 CN claimed
CN-103910590-A Biaryl compound and preparation method thereof UNIV SHAOXING 2014-07-09 CN claimed
CN-102381917-B Preparation method of biphenyl compound ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2013-11-06 CN claimed
CN-103172479-A Preparation method for biaryl through palladium catalysis UNIV SHAOXING 2013-06-26 CN claimed
CN-102381917-A Preparation method of biphenyl compound ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2012-03-21 CN claimed
EP-4545586-A1 FLUOROPOLYETHER GROUP-CONTAINING POLYMER, SURFACE TREATMENT AGENT, AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-30 EP disclosed
CN-119421916-A Fluoropolyether group-containing polymer, surface treatment agent and article 信越化学工业株式会社 2025-02-11 CN disclosed
CN-118122373-A Catalyst, preparation method thereof and application of catalyst in preparation of 2-aminopropanol by catalyzing acetol 中国科学院大连化学物理研究所 2024-06-04 CN disclosed
CN-110036318-A The manufacturing method of black matrix composition, black matrix and black matrix 夏普株式会社 2019-07-19 CN disclosed
CN-105531324-B Curable composition, cured product, and method for using curable composition 琳得科株式会社 2018-09-21 CN disclosed
CN-104903409-B Heat resistance decoration coloured composition, the manufacture method of capacitive input device and capacitive input device and possesses this image display device 富士胶片株式会社 2017-08-11 CN disclosed
CN-102381917-B Preparation method of biphenyl compound ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2013-11-06 CN disclosed
CN-103172479-A Preparation method for biaryl through palladium catalysis UNIV SHAOXING 2013-06-26 CN disclosed
CN-102754034-A Composition for formation of resist underlayer film containing silicon having nitrogen-containing ring NISSAN CHEMICAL IND LTD 2012-10-24 CN disclosed
CN-102597879-A Photosensitive resin composition ADEKA CORP 2012-07-18 CN disclosed
CN-102381917-A Preparation method of biphenyl compound ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2012-03-21 CN disclosed
CN-101260081-B Preparation method for N-arylazoles compounds UNIV ZHEJIANG 2011-04-13 CN disclosed
CN-101260081-A Preparation method for N-arylazoles compounds UNIV ZHEJIANG (CN) 2008-09-10 CN disclosed