SCHEMBL37363

SCHEMBL37363

CO[Si](OC)(OC)c1ccc(CCN)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 10/20 0.55
MAOB P27338 2/20 0.50
CYP2A6 P11509 2/20 0.50
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
HTR2A P28223 4/20 0.45
LOXL2 Q9Y4K0 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
SLC6A2 P23975 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR3A P46098 1/20 0.45
BACE1 P56817 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225261 0.83 TAAR1 (0.36) TAAR1MAOBCYP2A6CYP1A2
SCHEMBL27736772 0.83 HRH3 (0.44) TAAR1MAOBLOXL2
SCHEMBL5488548 0.81 LPL (0.42) ALDH1A1L3MBTL1
SCHEMBL17529734 0.81 ALDH1A1 (0.41) TAAR1MAOBALDH1A1
SCHEMBL2954273 0.81 TAAR1 (0.33) TAAR1MAOB
SCHEMBL5012011 0.81 SIGMAR1 (0.43)
SCHEMBL2946272 0.79 TDP1 (0.43) TAAR1KMT2ATDP1
SCHEMBL8826588 0.79 IDO1 (0.34) TAAR1
SCHEMBL20584032 0.78 LTA4H (0.41) KDM4EATMALDH1A1KMT2ATDP1
SCHEMBL2464561 0.78 CA2 (0.46) KDM4EHTR2AALDH1A1ADRA2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2576472-B1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2016-03-23 EP claimed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US claimed
EP-2576472-A2 ANTIMICROBIAL COATINGS 3M Innovative Properties Company (US) 2013-04-10 EP claimed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
US-20120015200-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
WO-2011150001-A2 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-01 WO claimed
WO-2011149998-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-01 WO claimed
US-12617970-B2 Urethane compounds comprising perfluorinated group, hydrolysable silane group, and (meth)acryl group 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-05 US disclosed
US-12291588-B2 Fluoropolymer compositions comprising a curing agent with ethylenically unsaturated and electron donor groups, and substrates coated therewith 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-05-06 US disclosed
US-20250004373-A1 FREE-RADICALLY POLYMERIZABLE COMPOUNDS, COMPOSITIONS INCLUDING THE SAME, POLYMERIZED COMPOUNDS, METHODS OF MAKING AND ARTICLES INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2025-01-02 US disclosed
CN-114600201-B Electronic communication articles and methods comprising crosslinked fluoropolymers 3M创新有限公司 2024-10-01 CN disclosed
US-20240318026-A1 COATING COMPOSITION COMPRISING A FLUOROPOLYMER AND A FLUORINATED ALCOHOL IN A FLUORINATED SOLVENT SUITABLE FOR ELECTRONIC COMMUNICATION ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2024-09-26 US disclosed
EP-3807369-B1 FLUOROPOLYMER COMPOSITIONS COMPRISING FLUORINATED ADDITIVES, COATED SUBSTRATES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-07-24 EP disclosed
US-20060147723-A1 Optically transmissive, stain and ink repellent, durable, optical display, coating, applied to substrates of articles used in the computer, television, appliance, mobile phone, aerospace and automotive industries 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US disclosed
US-20060147177-A1 Fluoropolymer coating compositions with olefinic silanes for anti-reflective polymer films 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US disclosed
US-20060148971-A1 Fluoropolymer nanoparticle coating composition 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US disclosed
WO-2006019650-A1 BONDING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-23 WO disclosed
WO-2006020573-A2 NONCARDIOTOXIC PHARMACEUTICAL COMPOUNDS BARBEAU DONALD L (US) 2006-02-23 WO disclosed
US-20050233150-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-10-20 US disclosed
US-20050208308-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617970-B2 Urethane compounds comprising perfluorinated group, hydrolysable silane group, and (meth)acryl group SSTR1, FFAR1, GFRA1 TAAR1 47/4885MAOB 1718/4885CYP2A6 2626/4885
US-20060147723-A1 Optically transmissive, stain and ink repellent, durable, optical display, coating, applied to substrates of articles used in the computer, television, appliance, mobile phone, aerospace and automotive industries PIR, MACF1, RAD54L TAAR1 12/4885MAOB 1838/4885CYP2A6 3922/4885
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN TAAR1 4128/4885MAOB 2531/4885CYP2A6 4115/4885
US-20060147177-A1 Fluoropolymer coating compositions with olefinic silanes for anti-reflective polymer films MKI67, EPCAM, ICAM1 TAAR1 873/4885MAOB 1514/4885CYP2A6 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.