Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 4/20 | 0.53 |
| ▸ | PDE1A | P54750 | 1/20 | 0.53 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.53 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454854 | 0.82 | ROCK2 (0.62) | ALDH1A1SCDPDE5AITGB1ITGA4 | |
| SCHEMBL7016372 | 0.81 | SCD (0.61) | ALDH1A1SCDMEN1KMT2AMME | |
| SCHEMBL14026892 | 0.81 | ELOVL1 (0.72) | ALDH1A1MEN1KMT2AELOVL1 | |
| Hydrochloric Acid SCHEMBL11311385 | 0.81 | MAPK1 (0.64) | ALDH1A1SCDKDM4E | |
| SCHEMBL7488591 | 0.79 | KMT2A (0.53) | ALDH1A1MEN1KMT2APDE5AITGB1 | |
| SCHEMBL8151940 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SCDMEN1KMT2APDE5A | |
| SCHEMBL15085702 | 0.78 | LMNA (0.51) | ALDH1A1MEN1KMT2AKDM4EELOVL1 | |
| SCHEMBL27743102 | 0.77 | MAPK1 (0.48) | ALDH1A1MEN1KMT2AKDM4EELOVL1 | |
| SCHEMBL5717756 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2APDE5AITGB1 | |
| SCHEMBL4832627 | 0.76 | ALDH1A1 (0.59) | ALDH1A1SCDPDE5AITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101445492-A | Amide thiazole derivant, preparation method and use thereof | TIANJIN INST PHARM RESEARCH (CN) | 2009-06-03 | — | — | CN | claimed |
| CN-101445492-A | Amide thiazole derivant, preparation method and use thereof | TIANJIN INST PHARM RESEARCH (CN) | 2009-06-03 | — | — | CN | disclosed |