Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16246881 | 0.76 | TAS1R3 (0.49) | ALDH1A1RAB9ATAS1R3TAS1R1HDAC8 | |
| SCHEMBL19296965 | 0.76 | MLYCD (0.59) | ALDH1A1CYP1A2HPGDCA2CA1 | |
| SCHEMBL14786715 | 0.73 | TAS1R3 (0.43) | HTTFOLH1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL1765101 | 0.73 | ALDH1A1 (0.42) | HTTFOLH1ALDH1A1RAB9ATAS1R3 | |
| SCHEMBL1363640 | 0.73 | MPO (0.64) | ALDH1A1CYP1A2CYP2D6CYP2C9CA2 | |
| SCHEMBL28453111 | 0.73 | HTT (0.47) | HTTFOLH1TAS1R3TAS1R1CA2 | |
| SCHEMBL27745006 | 0.72 | MLYCD (0.47) | FOLH1CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL7715145 | 0.72 | FOLH1 (0.50) | FOLH1ALDH1A1HDAC6CYP1A2CYP2D6 | |
| SCHEMBL28863365 | 0.71 | MEN1 (0.53) | ALDH1A1RAB9ATAS1R3TAS1R1HDAC6 | |
| SCHEMBL14715137 | 0.71 | TPMT (0.50) | FOLH1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472916-A | Chemical compounds | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | disclosed |