Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | CDC7 | O00311 | 4/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506448 | 0.77 | PTPRC (0.49) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL5618155 | 0.77 | TGFBR1 (0.71) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL5879310 | 0.77 | FLT3 (0.49) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL16705131 | 0.75 | FLT3 (0.67) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL1158441 | 0.75 | PTPRC (0.60) | PIM1CDK2PRKACAGSK3BKMT2A | |
| SCHEMBL27769958 | 0.74 | DYRK1A (0.52) | CAMKK2PDPK1IKBKEPIM1CDK2 | |
| SCHEMBL5879209 | 0.73 | PIM1 (0.49) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL1050911 | 0.72 | TGFBR1 (0.60) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL27750365 | 0.71 | PTPN11 (0.45) | DYRK1A | |
| SCHEMBL5879226 | 0.70 | FLT3 (0.57) | CAMKK2TGFBR1PDPK1IKBKEPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101492465-A | 7,7'-diaza indirubin compounds for antineoplastic medicament | UNIV SHANGHAI JIAOTONG (CN) | 2009-07-29 | — | — | CN | disclosed |