Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | CDC7 | O00311 | 4/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705131 | 0.81 | FLT3 (0.67) | FLT3KDRCAMKK2TGFBR1PDPK1 | |
| SCHEMBL5618155 | 0.77 | TGFBR1 (0.71) | FLT3CAMKK2TGFBR1PDPK1IKBKE | |
| SCHEMBL27748684 | 0.77 | CAMKK2 (0.48) | FLT3KDRCAMKK2TGFBR1PDPK1 | |
| SCHEMBL5879226 | 0.75 | FLT3 (0.57) | FLT3KDRCAMKK2TGFBR1PDPK1 | |
| SCHEMBL29771997 | 0.75 | PRKCB (0.65) | FLT3KDRPIM1CDK2PRKACA | |
| SCHEMBL2193383 | 0.75 | PRKCB (0.65) | FLT3KDRPIM1CDK2PRKACA | |
| SCHEMBL28506448 | 0.74 | PTPRC (0.49) | CAMKK2TGFBR1PDPK1IKBKEPIM1 | |
| SCHEMBL13596802 | 0.74 | PRKCB (0.72) | FLT3KDRTGFBR1PDPK1IKBKE | |
| SCHEMBL5879209 | 0.73 | PIM1 (0.49) | FLT3KDRCAMKK2TGFBR1PDPK1 | |
| SCHEMBL1050911 | 0.72 | TGFBR1 (0.60) | FLT3CAMKK2TGFBR1PDPK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7151108-B2 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATORIES SERVIER (FR) | 2006-12-19 | — | — | US | disclosed |
| EP-1411057-B1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-04-27 | — | — | EP | disclosed |
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATOIRES SERVIER (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1411057-A1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2004-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | XDH, TOP2A, TOP1 | FLT3 3152/4885KDR 2824/4885CAMKK2 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.