Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642534 | 0.85 | GABRP (0.58) | ALDH1A1LMNAKMT2AGABRA1GABRG2 | |
| SCHEMBL12500666 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1LMNAKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL10641678 | 0.84 | GABRP (0.57) | ALDH1A1LMNAKMT2AGABRA1GABRG2 | |
| SCHEMBL10644635 | 0.82 | KDM4E (0.58) | ALDH1A1LMNAKMT2AGABRA1GABRG2 | |
| SCHEMBL2492034 | 0.81 | CYP3A4 (0.51) | ALDH1A1LMNAKMT2AGABRA1GABRG2 | |
| SCHEMBL10642551 | 0.80 | PARP1 (0.49) | ALDH1A1TDP1KMT2AGABRA1GABRG2 | |
| SCHEMBL21027367 | 0.76 | TDP1 (0.54) | ALDH1A1TDP1LMNAKMT2ATSHR | |
| SCHEMBL10644994 | 0.76 | PBRM1 (0.46) | ALDH1A1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL7384110 | 0.75 | GABRA1 (0.56) | ALDH1A1TDP1LMNAKMT2AGABRA1 | |
| SCHEMBL901440 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591348-B | Tetrahydrochysene carboline acyl aminoacid benzyl ester, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2011-07-27 | — | — | CN | disclosed |
| CN-101591348-A | Tetrahydrochysene carboline acyl aminoacid benzyl ester and its production and application | UNIV CAPITAL MEDICAL (CN) | 2009-12-02 | — | — | CN | disclosed |