Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.42 |
| ▸ | GABRE | P78334 | 4/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642534 | 0.84 | GABRP (0.58) | KDM4EALDH1A1TSHRGABRPGABRD | |
| Hydrochloric Acid SCHEMBL10641678 | 0.82 | GABRP (0.57) | KDM4EALDH1A1TSHRGABRPGABRD | |
| SCHEMBL10644635 | 0.81 | KDM4E (0.58) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL27763175 | 0.81 | ALDH1A1 (0.47) | CYP3A4MAPK1ALDH1A1TSHRGABRP | |
| SCHEMBL10644994 | 0.77 | PBRM1 (0.46) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL10642551 | 0.76 | PARP1 (0.49) | KDM4EHSD17B10MAPK1ALDH1A1GABRP | |
| SCHEMBL8209973 | 0.73 | GABRA1 (0.72) | CYP3A4KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL3265121 | 0.72 | CYP3A4 (0.61) | CYP3A4HSD17B10ALDH1A1TSHRMEN1 | |
| SCHEMBL30388638 | 0.72 | CYP3A4 (0.61) | CYP3A4HSD17B10ALDH1A1TSHRMEN1 | |
| SCHEMBL17386427 | 0.72 | CYP3A4 (0.76) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |
| US-10106540-B2 | HDAC6 inhibitors and their uses | UNIVERSITÄT REGENSBURG (DE) | 2018-10-23 | — | — | US | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-2550063-A1 | ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE | Council of Scientific & Industrial Research (IN) | 2013-01-30 | — | — | EP | disclosed |
| US-20120245357-A1 | ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-09-27 | — | — | US | disclosed |
| WO-2011117706-A1 | ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | HDAC6, HDAC5, HDAC4 | CYP3A4 4529/4885KDM4E 676/4885HSD17B10 456/4885 |
| US-10106540-B2 | HDAC6 inhibitors and their uses | HDAC6, HDAC5, HDAC4 | CYP3A4 4365/4885KDM4E 608/4885HSD17B10 472/4885 |
| US-20120245357-A1 | ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE | INSRR, AGTR2, ERG28 | CYP3A4 4240/4885KDM4E 3864/4885HSD17B10 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.