Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.57 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705964 | 0.82 | LTB4R (0.46) | DAOLTB4RSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28521994 | 0.78 | DAO (0.59) | DAOLTB4RNOS1MAOAMAOB | |
| SCHEMBL8225698 | 0.77 | DAO (0.57) | DAOLTB4RNOS1MAOAMAOB | |
| SCHEMBL1244005 | 0.76 | DAO (0.60) | DAOLTB4RNOS1MAOAMAOB | |
| SCHEMBL1243895 | 0.73 | DAO (0.57) | DAOLTB4RNOS1MAOAMAOB | |
| SCHEMBL28528770 | 0.73 | DAO (0.57) | DAOLTB4RNOS1MAOAMAOB | |
| SCHEMBL1244006 | 0.73 | DAO (0.53) | DAOLTB4RMAOBNPC1RAB9A | |
| SCHEMBL13841376 | 0.71 | — | — | |
| SCHEMBL23487472 | 0.70 | MAOA (0.46) | MAOAMAOBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8196751 | 0.69 | SIGMAR1 (0.58) | MAOAMAOBCYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573364-A | Process for the preparation of 4-hydroxythieno [2, 3-b ] pyridine-5-carbonitriles | WYETH CORP (US) | 2009-11-04 | — | — | CN | disclosed |