Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783455 | 0.79 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL7474872 | 0.75 | CYP3A4 (0.40) | TSHRALDH1A1KMT2APOLBHTT | |
| SCHEMBL1847048 | 0.75 | PKM (0.37) | TSHRALDH1A1KMT2A | |
| SCHEMBL6688749 | 0.74 | THRB (0.31) | TSHRALDH1A1CES2CES1NPSR1 | |
| SCHEMBL27976403 | 0.72 | HTT (0.39) | TSHRALDH1A1KMT2ANPSR1POLB | |
| SCHEMBL9752038 | 0.71 | — | — | |
| SCHEMBL31567994 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28531913 | 0.71 | KDM1A (0.40) | — | |
| SCHEMBL8428534 | 0.71 | ABCB1 (0.36) | TSHRALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL11792991 | 0.70 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563322-A | 1H-indole-2-carboxylic acid derivatives useful as PPAR modulators | SMITHKLINE BEECHAM CORPORAITON (US) | 2009-10-21 | — | — | CN | disclosed |