Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769709 | 0.80 | ALK (0.41) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL358629 | 0.79 | MAPT (0.45) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28038009 | 0.78 | PTGES (0.45) | PTGESKMT2AALDH1A1HTTGABRA1 | |
| SCHEMBL28468025 | 0.74 | EGFR (0.42) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL358123 | 0.73 | EGFR (0.42) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1557518 | 0.73 | LMNA (0.41) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20319134 | 0.73 | CTSB (0.42) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28573345 | 0.73 | KMT2A (0.49) | PTGESMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9159295 | 0.72 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL27655698 | 0.72 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796099-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-101495477-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-29 | — | — | CN | disclosed |