Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A1 | P53007 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.64 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 4/20 | 0.62 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.61 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.61 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000258 | 1.00 | SLC25A1 (1.00) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL29918322 | 1.00 | SLC25A1 (1.00) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL30777865 | 1.00 | SLC25A1 (1.00) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL10389335 | 0.86 | SLC25A1 (0.75) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL27770307 | 0.84 | MEN1 (0.78) | SLC25A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL34475240 | 0.84 | MEN1 (0.78) | SLC25A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL31404880 | 0.84 | SLC25A1 (0.72) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL13146602 | 0.82 | SLC25A1 (0.69) | SLC25A1KMT2ALMNADNMT1DNMT3A | |
| SCHEMBL11749307 | 0.81 | SLC25A1 (0.68) | SLC25A1MEN1KMT2ALMNADNMT1 | |
| SCHEMBL10695037 | 0.81 | MEN1 (0.73) | SLC25A1MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767913-B | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2022-10-14 | — | — | CN | claimed |
| CN-113767913-A | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2021-12-10 | — | — | CN | claimed |
| US-12016834-B2 | Small molecule inhibitors of SLC25A1 | GEORGETOWN UNIVERSITY (US) | 2024-06-25 | — | — | US | disclosed |
| EP-3792251-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2024-02-14 | — | — | EP | disclosed |
| CN-113767913-B | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113767913-B | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| US-20220323389-A1 | TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND INFLAMMATORY STEATOHEPATITIS WITH SLC25A1 INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2022-10-13 | — | — | US | disclosed |
| CN-113767913-A | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-113767913-A | Application of 2- [ (4-chloro-3-nitrophenyl) sulfonamide ] benzoic acid in preparation of insect growth regulator | 上海应用技术大学 | 2021-12-10 | — | — | CN | disclosed |
| US-20200246285-A1 | SMALL MOLECULE INHIBITORS OF SLC25A1 | GEORGETOWN UNIVERSITY (US) | 2020-08-06 | — | — | US | disclosed |
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-7119120-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-10-10 | — | — | US | disclosed |
| EP-1465638-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040019113-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003057225-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019113-A1 | Phosphate transport inhibitors | SLC34A1, SLC34A2, SLC20A1 | SLC25A1 103/4885MEN1 2905/4885KMT2A 4536/4885 |
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | SLC25A1 108/4885MEN1 2248/4885KMT2A 4634/4885 |
| US-20220323389-A1 | TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND INFLAMMATORY STEATOHEPATITIS WITH SLC25A1 INHIBITORS | SLC10A1, SLC27A1, SLC25A3 | SLC25A1 16/4885MEN1 4426/4885KMT2A 2418/4885 |
| US-20200246285-A1 | SMALL MOLECULE INHIBITORS OF SLC25A1 | SLC25A3, SLC2A1, SLC2A2 | SLC25A1 5/4885MEN1 1861/4885KMT2A 2170/4885 |
| US-12016834-B2 | Small molecule inhibitors of SLC25A1 | SLC25A3, SLC2A1, SLC2A2 | SLC25A1 5/4885MEN1 1861/4885KMT2A 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.