Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325401 | 0.88 | PKM (0.70) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL31352975 | 0.88 | MTNR1B (0.56) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL3151230 | 0.88 | MTNR1B (0.56) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL14282636 | 0.86 | PGR (0.56) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL14282635 | 0.85 | HTT (0.59) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL8865965 | 0.83 | LMNA (0.56) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL27770545 | 0.82 | PKM (0.79) | PKMGAAALDH1A1POLB | |
| SCHEMBL18164882 | 0.81 | ABCC9 (0.55) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL8866738 | 0.80 | KMT2A (0.58) | MTNR1BPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL2959233 | 0.78 | PGR (0.72) | PKMNFE2L2KEAP1FFAR4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |