Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781756 | 0.89 | MAOB (0.44) | MAOBMAOASGMS2 | |
| SCHEMBL27792413 | 0.86 | NPC1 (0.49) | MAOBLRRK2 | |
| SCHEMBL27792405 | 0.81 | KMT2A (0.47) | MAOBMAOA | |
| SCHEMBL27771260 | 0.76 | FADS1 (0.52) | MAOBMAOAFADS1 | |
| SCHEMBL27792361 | 0.74 | KCNMA1 (0.66) | MAOBMAOASGMS2FADS1 | |
| SCHEMBL27792464 | 0.70 | KCNMA1 (0.55) | MAOBMAOA | |
| SCHEMBL3654708 | 0.69 | — | — | |
| SCHEMBL15903292 | 0.68 | RXFP1 (0.52) | SGMS2 | |
| SCHEMBL27771292 | 0.68 | SGMS2 (0.52) | MAOBMAOASGMS2LRRK2 | |
| SCHEMBL27936605 | 0.67 | MAOB (0.65) | MAOBMAOAFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |