SCHEMBL27775985

SCHEMBL27775985

Cn1c(Cc2ccccc2)nc(O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.48
LTB4R Q15722 1/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HTR6 P50406 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 1/20 0.38
CALM1 P0DP23 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27867318 0.75 LTB4R (0.50) RXFP1LTB4RALDH1A1HRH4KMT2A
SCHEMBL2518498 0.71 LMNA (0.63) NPC1RAB9AALDH1A1KMT2ALMNA
SCHEMBL9275701 0.71 LTB4R (0.46) RXFP1LTB4RALDH1A1LMNAKDM4E
SCHEMBL33657 0.68 ATM (0.45) NPC1RAB9AALDH1A1KMT2AHTT
SCHEMBL5483849 0.68 SMN1; SMN2 (0.48) ALDH1A1KMT2AHPGDSMN1; SMN2CALM1
SCHEMBL468709 0.68 LTB4R (0.46) LTB4RNPC1HRH4KMT2AHPGD
Arborine SCHEMBL1150473 0.67 KDM4E (0.55) RXFP1NPC1RAB9AALDH1A1KMT2A
SCHEMBL6759188 0.67 MEN1 (0.48) RXFP1LTB4RNPC1RAB9AKMT2A
SCHEMBL21332672 0.66 ATM (0.57) RXFP1NPC1RAB9AALDH1A1KMT2A
SCHEMBL17231383 0.66 ADRB2 (0.44) RXFP1LTB4RKMT2ALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101679721-A Resin composition, filling material, insulating layer and semiconductor device SUMITOMO BAKELITE CO 2010-03-24 CN disclosed