Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919017 | 0.76 | EPHX2 (0.35) | MEN1KMT2AEPHX2CHRNB2CHRNA4 | |
| SCHEMBL12253322 | 0.75 | NOS3 (0.34) | MEN1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL13930554 | 0.71 | SRD5A1 (0.43) | MEN1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL12616857 | 0.71 | CTSL (0.35) | MEN1KMT2AEPHX2CHRNB2CHRNA4 | |
| SCHEMBL3153525 | 0.67 | TRPM5 (0.41) | MEN1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL12253324 | 0.66 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL464509 | 0.65 | EPHX2 (0.37) | MEN1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL7992775 | 0.64 | EPHX2 (0.42) | MEN1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL12253323 | 0.64 | RAB9A (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27267001 | 0.61 | KMT2A (0.35) | MEN1KMT2AALDH1A1EPHX2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1499609-A4 | PESTICIDAL HETEROCYCLES | FMC CORP (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050143418-A1 | Pesticidal heterocycles | FMC CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1499609-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092374-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | MEN1 705/4885KMT2A 3878/4885ALDH1A1 4036/4885 |
| US-20050143418-A1 | Pesticidal heterocycles | DDT, TRHR, ACHE | MEN1 611/4885KMT2A 3837/4885ALDH1A1 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.