Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27568992 | 0.98 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Toluene SCHEMBL10442875 | 0.80 | LMNA (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Toluene SCHEMBL11282535 | 0.80 | NOS1 (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27443748 | 0.77 | ALDH1A1 (0.35) | MEN1KMT2ATDP1MAPTCYP3A4 | |
| SCHEMBL942161 | 0.75 | — | — | |
| M-Xylene SCHEMBL29091465 | 0.75 | ACHE (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30102207 | 0.74 | MEN1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30332449 | 0.74 | MEN1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1405327 | 0.74 | MEN1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11981455 | 0.74 | MEN1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056799-B | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, application and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-108690371-A | A kind of salt-free liquid dyes of double vinyl-sulfone reactives, preparation method and application | 天津晶丽数码科技有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-101528710-B | Aminomethyl-4-imidazoles | HOFFMANN LA ROCHE | 2012-11-07 | — | — | CN | disclosed |
| CN-101528710-A | Aminomethyl-4-imidazoles | HOFFMANN LA ROCHE (CH) | 2009-09-09 | — | — | CN | disclosed |