Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1669168 | 0.89 | KDM4E (0.46) | ALDH1A1KDM4EMAPTMAOAGAA | |
| SCHEMBL2776103 | 0.84 | HPGD (0.35) | ALDH1A1KDM4EMAPTMAOAGAA | |
| SCHEMBL9448317 | 0.77 | KDM4E (0.43) | KDM4EMAPTMAPK1HSD17B10MEN1 | |
| SCHEMBL5981019 | 0.74 | MPO (0.48) | ALDH1A1KDM4EMAPTMAOAABCB1 | |
| SCHEMBL8791849 | 0.74 | MPO (0.59) | ALDH1A1KDM4EMAPTGAAMAPK1 | |
| SCHEMBL17028333 | 0.69 | HTR2A (0.42) | — | |
| SCHEMBL10835651 | 0.69 | KDM4E (0.38) | ALDH1A1KDM4EMAPTHPGDMAPK1 | |
| SCHEMBL21360714 | 0.68 | MAOA (0.56) | ALDH1A1KDM4EMAPTMAOAGAA | |
| SCHEMBL10751721 | 0.68 | SMN1; SMN2 (0.33) | ALDH1A1KDM4EMAPTALOX15CASP1 | |
| SCHEMBL9448055 | 0.68 | SIGMAR1 (0.41) | ALDH1A1KDM4EMAPTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1499609-A4 | PESTICIDAL HETEROCYCLES | FMC CORP (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050143418-A1 | Pesticidal heterocycles | FMC CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1499609-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092374-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | ALDH1A1 4036/4885KDM4E 3146/4885MAPT 1462/4885 |
| US-20050143418-A1 | Pesticidal heterocycles | DDT, TRHR, ACHE | ALDH1A1 3938/4885KDM4E 3256/4885MAPT 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.