SCHEMBL27780798

SCHEMBL27780798

CCNCC[SiH](CC)C(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.31
GLA P06280 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM1A O60341 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849042 0.75 LMNA (0.47) LMNA
Ammonia Solution, Strong SCHEMBL17800302 0.68 MEN1 (0.34) LMNAMEN1KMT2ACYP1A2
SCHEMBL2270165 0.67 TSHR (0.37) CYP2C19MEN1GLAKMT2AKDM1A
SCHEMBL8849111 0.66 THRB (0.38) LMNA
SCHEMBL2276021 0.64 TSHR (0.39) CYP2C19MEN1GLAKMT2AKDM1A
SCHEMBL13185663 0.63 CYP2C19 (0.38) LMNACYP2C19MEN1GLAKMT2A
SCHEMBL8849027 0.63 THRB (0.35) LMNA
SCHEMBL4237452 0.63 CYP2C19 (0.38) CYP2C19MEN1GLAKMT2AKDM1A
SCHEMBL1818524 0.63 LMNA (0.35) LMNA
SCHEMBL16213696 0.61 LMNA (0.38) LMNACYP2C19MEN1GLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102199316-B Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND 2014-12-17 CN disclosed
CN-101747538-B Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER IND 2013-05-01 CN disclosed
CN-101735498-B Rubber composition and tire SUMITOMO RUBBER IND 2013-03-13 CN disclosed
CN-102199316-A Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND 2011-09-28 CN disclosed
CN-101747538-A Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER IND 2010-06-23 CN disclosed
CN-101735498-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-16 CN disclosed
CN-101712776-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2010-05-26 CN disclosed