Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807916 | 0.96 | ACHE (0.31) | ACHE | |
| SCHEMBL27785941 | 0.89 | — | — | |
| SCHEMBL27785931 | 0.85 | — | — | |
| SCHEMBL27786000 | 0.84 | MAPK10 (0.36) | — | |
| SCHEMBL27785961 | 0.84 | CHRNB2 (0.33) | ACHE | |
| SCHEMBL27785937 | 0.82 | ADORA2A (0.32) | — | |
| SCHEMBL27807943 | 0.82 | — | — | |
| SCHEMBL27786011 | 0.81 | BRD9 (0.36) | — | |
| SCHEMBL27807930 | 0.80 | MAPK10 (0.36) | — | |
| SCHEMBL27807950 | 0.79 | HRH4 (0.32) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | claimed |
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |