Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807969 | 0.88 | HRH4 (0.34) | HRH4CRHR1 | |
| SCHEMBL27807911 | 0.86 | HRH4 (0.35) | TLR7HRH4CRHR1 | |
| SCHEMBL28787429 | 0.85 | HRH4 (0.35) | HRH4CRHR1 | |
| SCHEMBL27786138 | 0.85 | GABRG2 (0.42) | CYP17A1 | |
| SCHEMBL28787406 | 0.83 | CD38 (0.33) | TLR7HRH4CRHR1 | |
| SCHEMBL27807992 | 0.83 | KDM4E (0.36) | TLR7 | |
| SCHEMBL27807928 | 0.82 | USP1 (0.38) | TLR7 | |
| SCHEMBL27807921 | 0.82 | CHRNB1 (0.37) | CYP11B1CYP11B2CYP17A1HRH4CHRNB1 | |
| SCHEMBL27785954 | 0.82 | GABRG2 (0.42) | — | |
| SCHEMBL27785944 | 0.81 | BCL2L11 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | claimed |
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |