Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024845 | 0.80 | PTGS1 (0.60) | HPGDLMNAMAPTPKMKDM4E | |
| SCHEMBL5553721 | 0.74 | AKR1C3 (0.44) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL5558582 | 0.74 | PTGS2 (0.47) | HTTHPGDLMNASMN1; SMN2PTGS1 | |
| SCHEMBL6025282 | 0.73 | PTGS1 (0.47) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL8673753 | 0.73 | HTR6 (0.43) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL27790010 | 0.73 | GAA (0.47) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL5799040 | 0.72 | PTGS2 (0.46) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL6025591 | 0.72 | PTGS2 (0.48) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL27905740 | 0.71 | CNR2 (0.41) | HTTHPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL6025108 | 0.70 | CNR2 (0.47) | HTTHPGDLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | disclosed |