Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Anthracene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL21582023 | 0.97 | LMNA (0.46) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Anthracene SCHEMBL31187000 | 0.97 | LMNA (0.46) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Anthracene SCHEMBL21295279 | 0.86 | L3MBTL1 (0.48) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Anthracene SCHEMBL28958017 | 0.86 | TSHR (0.44) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL29361795 | 0.84 | ALOX12 (0.57) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL28674544 | 0.84 | ALOX12 (0.57) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL5574575 | 0.84 | ALOX12 (0.57) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL672294 | 0.84 | ALOX12 (0.57) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL2678900 | 0.84 | ALOX12 (0.57) | LMNATSHRSMN1; SMN2CES2CES1 | |
| Naphthalene SCHEMBL9484717 | 0.81 | ALOX12 (0.53) | LMNATSHRSMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104677895-B | A kind of method for determining Chinese chestnut content of starch | 山东省果树研究所 | 2017-07-25 | — | — | CN | claimed |
| CN-104677895-A | Method for measuring starch content of Chinese chestnut | SHANDONG INST POMOLOGY | 2015-06-03 | — | — | CN | claimed |
| CN-111621467-A | Method for inducing human adipose-derived mesenchymal stem cells to differentiate into liver-like cells | 青岛大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-110100949-A | A kind of application of feeding Chinese medicine composition microflora fermentation method and its product | 甘肃联邦生物科技有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-108795800-A | The lactobacillus plantarum of one plant of production feruloyl esterase | 兰州大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-108330072-A | Inonotus obliquus liquid submerged fermentation culture composition and preparation method and application thereof | 山西康欣药业有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108300629-A | A kind of mulberries blueberry wine and its production technology | 江苏省农业科学院 | 2018-07-20 | — | — | CN | disclosed |
| CN-108251250-A | A kind of strawberry fruit wine and its production technology | 江苏省农业科学院 | 2018-07-06 | — | — | CN | disclosed |
| CN-108251251-A | A kind of Yangtao wine and its production technology | 江苏省农业科学院 | 2018-07-06 | — | — | CN | disclosed |
| CN-104830696-B | A kind of high yield CNNS Marasmius mutagenic strain and breeding method | 吉林大学 | 2018-05-22 | — | — | CN | disclosed |
| CN-104877917-B | A kind of Antrodia camphorata mutagenic strain and breeding method | 吉林大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-104208581-A | Schisandra chinensis health care oral liquid capable of preventing alcoholic liver and preparation method thereof | QINGDAO HENGBO INSTR CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-102559513-B | High-yield Irpex lacteus mutant strain and culture method thereof | UNIV JILIN | 2013-05-01 | — | — | CN | disclosed |
| CN-102533567-B | Paecilomyces tenuipes mutagenesis bacterial strain and culturing method thereof | UNIV JILIN | 2013-05-01 | — | — | CN | disclosed |
| CN-102559513-A | High-yield Irpex lacteus mutant strain and culture method thereof | UNIV JILIN | 2012-07-11 | — | — | CN | disclosed |
| CN-102533567-A | Paecilomyces tenuipes mutagenesis bacterial strain and culturing method thereof | UNIV JILIN | 2012-07-04 | — | — | CN | disclosed |
| CN-101690463-B | Mutagenic strain of cordyceps militaris and breeding method | UNIV JILIN | 2012-06-27 | — | — | CN | disclosed |
| CN-101695645-B | Reverse micelle as well as preparation method and application to cellulose enzymolysis thereof | UNIV HUNAN | 2012-03-14 | — | — | CN | disclosed |
| CN-101695645-A | Reverse micelle as well as preparation method and application to cellulose enzymolysis thereof | UNIV HUNAN | 2010-04-21 | — | — | CN | disclosed |
| CN-101690463-A | Mutagenic strain of cordyceps militaris and breeding method | UNIV JILIN | 2010-04-07 | — | — | CN | disclosed |