Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Anthracene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 known ✓ | P00734 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL21582023 | 0.88 | LMNA (0.46) | L3MBTL1CA1CA2LMNASNCA | |
| Anthracene SCHEMBL31187000 | 0.88 | LMNA (0.46) | L3MBTL1CA1CA2LMNASNCA | |
| Naphthalene SCHEMBL476327 | 0.88 | ALOX12 (0.50) | L3MBTL1SLC2A1ATMKEAP1CA1 | |
| Naphthalene SCHEMBL27549394 | 0.86 | ALOX12 (0.47) | L3MBTL1SLC2A1ATMKEAP1CA1 | |
| Naphthalene SCHEMBL20496113 | 0.86 | ALOX12 (0.47) | L3MBTL1SLC2A1ATMKEAP1CA1 | |
| Anthracene SCHEMBL27800684 | 0.86 | LMNA (0.44) | L3MBTL1CA1CA2LMNASNCA | |
| Acridine SCHEMBL8000372 | 0.84 | ALDH1A1 (0.65) | LMNASMN1; SMN2KMT2ATDP1 | |
| Anthracene SCHEMBL28958017 | 0.83 | TSHR (0.44) | L3MBTL1CA1CA2LMNASNCA | |
| Anthracene SCHEMBL31722820 | 0.82 | CYP1A2 (0.43) | L3MBTL1SLC2A1PTGS2CA1CA2 | |
| Betanaphthol SCHEMBL27615211 | 0.82 | CYP1A2 (0.71) | L3MBTL1ATMCA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019162492-A1 | FLUORINATED MONOMERS COMPRISING ANTHRACENE MOIETIES | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2019-08-29 | — | — | WO | disclosed |