⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752197 | 0.75 | RXRA (0.38) | — | |
| SCHEMBL2751572 | 0.71 | TLR8 (0.33) | — | |
| SCHEMBL2749869 | 0.67 | RXRA (0.41) | — | |
| SCHEMBL102848 | 0.59 | CES2 (0.40) | — | |
| SCHEMBL208411 | 0.59 | — | — | |
| SCHEMBL2686979 | 0.59 | — | — | |
| SCHEMBL23174652 | 0.57 | CES2 (0.39) | — | |
| SCHEMBL28642337 | 0.57 | CES2 (0.39) | — | |
| SCHEMBL29121446 | 0.57 | CES2 (0.39) | — | |
| SCHEMBL63468 | 0.57 | ALDH1A1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078217-A1 | TETRACENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院化学研究所 | 2021-04-29 | — | — | WO | claimed |
| CN-112694388-A | Naphthacene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-23 | — | — | CN | claimed |
| CN-1662508-A | Compounds, compositions and methods | CYTOKINETICS INC (US) | 2005-08-31 | — | — | CN | claimed |
| WO-2021078217-A1 | TETRACENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院化学研究所 | 2021-04-29 | — | — | WO | disclosed |
| CN-112694388-A | Naphthacene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-23 | — | — | CN | disclosed |
| EP-2857396-B1 | FUSED HETEROCYCLIC COMPOUNDS FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2018-11-21 | — | — | EP | disclosed |
| EP-2952096-B1 | Amide compound, an arthropod pest control agent and a method for controlling arthropod pest | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9814235-B2 | Method for controlling arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-14 | — | — | US | disclosed |
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| CN-104334552-B | Fused heterocyclic compound | 住友化学株式会社 | 2016-08-31 | — | — | CN | disclosed |
| EP-2373648-B1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YL ACETIC ACIDS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1819692-A1 | 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |
| WO-2006062240-A1 | 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-06-15 | — | — | WO | disclosed |
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| CN-1726198-A | Compounds, compositions, and methods | CYTOKINETICS INC (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1662508-A | Compounds, compositions and methods | CYTOKINETICS INC (US) | 2005-08-31 | — | — | CN | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |