Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963119 | 0.85 | LMNA (0.45) | CYP11B1CYP11B2LMNAMMEL3MBTL1 | |
| SCHEMBL27963122 | 0.83 | MME (0.42) | LMNAMMEMAPTRAB9A | |
| SCHEMBL27963121 | 0.81 | MAPT (0.42) | MMEMAPTL3MBTL1TP53POLB | |
| SCHEMBL27963148 | 0.79 | MAPT (0.39) | CYP11B1CYP11B2LMNAMMEMAPT | |
| SCHEMBL27657760 | 0.74 | MAPT (0.40) | LMNAMMEMAPTGAATP53 | |
| SCHEMBL27963156 | 0.73 | MAPT (0.53) | LMNAMMEMAPTGAACYP2C9 | |
| SCHEMBL27809130 | 0.73 | ALDH1A1 (0.35) | MAPTL3MBTL1KDM4EGAARAB9A | |
| SCHEMBL27815832 | 0.72 | MAPT (0.37) | LMNAMMEMAPTGAAADORA3 | |
| SCHEMBL27815972 | 0.72 | LMNA (0.38) | CYP11B1CYP11B2LMNAMMEMAPT | |
| SCHEMBL28014533 | 0.70 | CYP2D6 (0.37) | CYP11B1CYP11B2LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-A | 1-aryl-3-aryl-1H-pyrromonazole-5-hydroximic acid derivative and application thereof | UNIV SHANDONG | 2014-05-14 | — | — | CN | disclosed |