Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963156 | 0.90 | MAPT (0.53) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL27963119 | 0.88 | LMNA (0.45) | LMNAPOLBRAB9APTPN1CYP11B1 | |
| SCHEMBL27963122 | 0.81 | MME (0.42) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL28030908 | 0.80 | CPA1 (0.46) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL27963175 | 0.79 | CYP11B1 (0.38) | MAPTLMNAPOLBRAB9APTPN1 | |
| SCHEMBL27963121 | 0.79 | MAPT (0.42) | MAPTMEN1KMT2ATDP1NPC1 | |
| SCHEMBL28172139 | 0.78 | CYP11B1 (0.52) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL27677335 | 0.76 | MEN1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29110788 | 0.74 | MAPT (0.51) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL27815972 | 0.72 | LMNA (0.38) | MAPTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-A | 1-aryl-3-aryl-1H-pyrromonazole-5-hydroximic acid derivative and application thereof | UNIV SHANDONG | 2014-05-14 | — | — | CN | disclosed |