Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738891 | 0.82 | EPHX1 (0.67) | EPHX1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL26413302 | 0.74 | RAB9A (0.70) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| Resorcinol SCHEMBL27980362 | 0.72 | PPIA (0.44) | PPIAEPHX2LMNA | |
| SCHEMBL6724549 | 0.70 | RAB9A (0.80) | EPHX1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL11316579 | 0.69 | RAB9A (0.60) | EPHX1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL3660554 | 0.69 | L3MBTL1 (0.65) | SMN1; SMN2RAB9ANPC1PKM | |
| Resorcinol SCHEMBL27796353 | 0.69 | MAOA (0.53) | EPHX1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL31280763 | 0.69 | RAB9A (0.60) | EPHX1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL4346187 | 0.69 | EPHX1 (0.63) | EPHX1SMN1; SMN2MEN1KMT2AHTT | |
| Resorcinol SCHEMBL28241681 | 0.69 | PARP1 (0.48) | MEN1KMT2ALMNAPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |