Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835194 | 0.86 | MAPT (0.57) | MAPTKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27815788 | 0.81 | ABCG2 (0.64) | ABCG2MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL27815707 | 0.80 | VCP (0.52) | MAPTKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1592702 | 0.79 | ABCG2 (0.57) | ABCG2MAPTSMN1; SMN2NFKB1APP | |
| SCHEMBL8978637 | 0.78 | NFKB1 (0.65) | ABCG2MAPTKMT2AALDH1A1NFKB1 | |
| SCHEMBL11405229 | 0.75 | ALDH1A1 (0.52) | MAPTKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30490523 | 0.72 | NFKB1 (0.53) | MAPTKMT2ANFKB1EGFRAGPAT2 | |
| SCHEMBL29609042 | 0.71 | NFKB1 (0.64) | MAPTKMT2ASMN1; SMN2NFKB1APP | |
| SCHEMBL13326017 | 0.71 | NFKB1 (0.64) | MAPTKMT2ASMN1; SMN2NFKB1APP | |
| SCHEMBL7564951 | 0.70 | KDR (0.58) | ABCG2EGFRABCB1ABCC1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102143953-A | Pyrimidines, triazines and their use as pharmaceutical agents | UNIV NOTTINGHAM | 2011-08-03 | — | — | CN | disclosed |