Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721904 | 1.00 | KMT2A (0.41) | KMT2ACYP1A2CNR2LMNAHSD17B10 | |
| SCHEMBL27820015 | 0.84 | LMNA (0.53) | KMT2ALMNAHSD17B10CRHBPCRHR2 | |
| SCHEMBL27953751 | 0.83 | CRHBP (0.41) | CYP1A2CNR2LMNAHSD17B10CRHBP | |
| SCHEMBL10443280 | 0.82 | KMT2A (0.43) | KMT2ACYP1A2CNR2LMNAHSD17B10 | |
| SCHEMBL25377657 | 0.82 | KMT2A (0.53) | KMT2ACYP1A2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL6766 | 0.82 | KMT2A (0.53) | KMT2ACYP1A2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9680703 | 0.81 | CYP1A2 (0.48) | KMT2ACYP1A2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL27580033 | 0.79 | RAB9A (0.36) | KMT2ACYP1A2LMNASMN1; SMN2RAB9A | |
| SCHEMBL9680223 | 0.77 | CYP1A2 (0.44) | KMT2ACYP1A2LMNAHSD17B10RAB9A | |
| SCHEMBL2720268 | 0.77 | ALOX5 (0.47) | KMT2ACYP1A2RAB9AMEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036955-B | Hydroxamate-based inhibitors of deacetylase B | NOVARTIS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-102036955-A | Hydroxamate-based inhibitors of deacetylase B | NOVARTIS AG | 2011-04-27 | — | — | CN | disclosed |