Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012725 | 0.89 | KDM4E (0.41) | CA2ALOX5BACE1CFDLMNA | |
| SCHEMBL3985018 | 0.88 | CYP4F2 (0.38) | CA2ALOX5BACE1CFDMAPT | |
| SCHEMBL29466877 | 0.83 | CA2 (0.53) | CA2ALOX5BACE1CFDLMNA | |
| SCHEMBL27852474 | 0.82 | AKT1 (0.46) | ALOX5BACE1CFDLMNAKDM4E | |
| SCHEMBL3083354 | 0.82 | LMNA (0.47) | ALOX5BACE1LMNAKDM4EHTT | |
| SCHEMBL27848177 | 0.80 | ABCB11 (0.45) | ALOX5BACE1LMNAKDM4EHTT | |
| SCHEMBL27671451 | 0.78 | LMNA (0.40) | CA2ALOX5BACE1LMNAKDM4E | |
| SCHEMBL4647729 | 0.77 | HSD17B10 (0.50) | CA2BACE1CFDKDM4EHTT | |
| SCHEMBL3187718 | 0.76 | CFD (0.50) | CFDLMNAKDM4EHTTHSD17B10 | |
| SCHEMBL19622461 | 0.76 | HTT (0.42) | ALOX5BACE1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421759-A | Pyridazinone compounds and use thereof | SUMITOMO CHEMICAL CO | 2012-04-18 | — | — | CN | disclosed |