Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 7/20 | 0.59 |
| ▸ | PKLR | P30613 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985955 | 0.96 | PARG (0.59) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29384291 | 0.96 | PKLR (0.62) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| Silver SCHEMBL11327330 | 0.96 | PARG (0.59) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28367628 | 0.96 | PKLR (0.62) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9235321 | 0.96 | PARG (0.59) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL32662068 | 0.96 | PKLR (0.62) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2858677 | 0.96 | PARG (0.59) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL305527 | 0.96 | PKLR (0.62) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| Water SCHEMBL30203790 | 0.94 | PKLR (0.60) | PARGPKLRKMT2ASMN1; SMN2MEN1 | |
| Water SCHEMBL1976332 | 0.94 | PKLR (0.60) | PARGPKLRKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107442167-B | Catalyst for preparing aromatic polycarboxylic acid by liquid phase oxidation | 中国石油化工股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| EP-2218715-B1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | SUMITOMO SEIKA CHEMICALS (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-8216768-B2 | Photoacid generator and photoreactive composition | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100233621-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2218715-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | Sumitomo Seika Chemicals CO. LTD. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-3974170-A | SULFONATES, SULFINATES | MONSANTO COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233621-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | ARSA, SULT1A1, CYBA | PARG 3130/4885PKLR 1773/4885KMT2A 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.