Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011414 | 0.77 | METAP2 (0.46) | METAP2PTPRC | |
| SCHEMBL27174135 | 0.77 | METAP2 (0.46) | METAP2PTPRC | |
| SCHEMBL51294 | 0.77 | METAP2 (0.46) | METAP2PTPRC | |
| SCHEMBL29360004 | 0.77 | METAP2 (0.46) | METAP2PTPRC | |
| SCHEMBL585349 | 0.74 | TDP1 (0.42) | METAP2MEN1THRBBLMKMT2A | |
| SCHEMBL68422 | 0.74 | MAOA (0.33) | — | |
| SCHEMBL24206 | 0.74 | MAOA (0.46) | METAP2MEN1KMT2A | |
| SCHEMBL9272539 | 0.71 | SIGMAR1 (0.39) | METAP2MEN1THRBBLMKMT2A | |
| SCHEMBL13959698 | 0.70 | ALDH1A1 (0.50) | METAP2MEN1THRBBLMKMT2A | |
| SCHEMBL17032342 | 0.69 | ALDH1A1 (0.43) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459280-A | Thieno [2,3-b ] pyridine derivatives as inhibitors of viral replication | UNIV LEUVEN KATH | 2012-05-16 | — | — | CN | disclosed |