SCHEMBL27856424

SCHEMBL27856424

C[SiH](CN)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.38
TAAR1 Q96RJ0 10/20 0.36
HTR2A P28223 2/20 0.35
CYP2A6 P11509 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HRH1 P35367 1/20 0.32
TP53 P04637 1/20 0.32
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
MAOA P21397 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5681511 0.77 MAOA (0.40) LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2
SCHEMBL2229742 0.76 TP53 (0.39) TP53
SCHEMBL2414663 0.74 TSHR (0.38) TP53CYP1A2
SCHEMBL68910 0.74 TSHR (0.32) TP53
SCHEMBL14366700 0.72 TP53 (0.36) LOXL2TAAR1TP53MAOACYP3A4
SCHEMBL8992405 0.72 TP53 (0.36) TP53
SCHEMBL9239449 0.72 TP53 (0.42) LOXL2TAAR1TP53MAOASLC6A2
SCHEMBL27746341 0.70 LOXL2 (0.39) LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2
SCHEMBL11654724 0.70 RIPK1 (0.33) TAAR1SLC6A2CYP3A4CYP2C19
SCHEMBL9746880 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102304229-B Method for preparing optically active poly(alkyl-aryl) silane UNIV HANGZHOU NORMAL 2012-10-24 CN disclosed
CN-102304229-A Method for preparing optically active poly(alkyl-aryl) silane UNIV HANGZHOU NORMAL 2012-01-04 CN disclosed