Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 17/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133327 | 0.84 | MRGPRX4 (0.49) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL13685883 | 0.82 | TMEM97 (0.53) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL4572223 | 0.80 | GLRA1 (0.41) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL4950108 | 0.80 | ALDH1A1 (0.48) | MRGPRX4 | |
| SCHEMBL10036558 | 0.80 | GLRA1 (0.41) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL39676 | 0.79 | TSHR (0.47) | MRGPRX4 | |
| SCHEMBL16240333 | 0.79 | PRSS1 (0.55) | TP53SMN1; SMN2RAB9ANPC1XBP1 | |
| SCHEMBL29472003 | 0.79 | TSHR (0.47) | MRGPRX4 | |
| SCHEMBL18412078 | 0.77 | ALDH1A1 (0.46) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL9929337 | 0.77 | ALDH1A1 (0.46) | MRGPRX4TP53NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120241373-A1 | COMPOSITE MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120012527-A1 | COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
| US-8063238-B2 | Diamine compound having phosphorylcholine group, polymer thereof, and process for producing the polymer | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20100239788-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100216899-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2010-08-26 | — | — | US | disclosed |
| WO-2010096563-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096565-A1 | INTERFACIAL POLYMERIZATION METHODS FOR MAKING FLUOROALCOHOL-CONTAINING POLYAMIDES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| US-20100216967-A1 | INTERFACIAL POLYMERIZATION METHODS FOR MAKING FLUOROALCOHOL-CONTAINING POLYAMIDES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100208180-A1 | Negative Birefringement Polyester Films For LCD | AKRON POLYMER SYSTEMS INC. | 2010-08-19 | — | — | US | disclosed |
| US-20100036081-A1 | Diamine Compound Having Phosphorylcholine Group, Polymer Thereof, and Process for Producing the Polymer | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-02-11 | — | — | US | disclosed |
| US-7351773-B2 | Polymerizable composition | FUJIFILM CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036081-A1 | Diamine Compound Having Phosphorylcholine Group, Polymer Thereof, and Process for Producing the Polymer | PHOSPHO1, PCTP, PDAP1 | MRGPRX4 2465/4885TP53 4662/4885NFKB1 4789/4885 |
| US-20100239788-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | PYM1, CCND2, CCNB2 | MRGPRX4 3706/4885TP53 2833/4885NFKB1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.