Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 12/20 | 0.50 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788674 | 0.88 | LTA4H (0.49) | LTA4HACHEBCHEFDPS | |
| SCHEMBL17156985 | 0.87 | LTA4H (0.66) | LTA4HACHEBCHE | |
| SCHEMBL2787271 | 0.83 | LTA4H (0.45) | LTA4HACHEBCHEFDPS | |
| SCHEMBL24675197 | 0.82 | KDM4E (0.43) | — | |
| SCHEMBL24674865 | 0.82 | KDM4E (0.43) | — | |
| SCHEMBL2790125 | 0.79 | ACHE (0.43) | LTA4HACHEBCHE | |
| SCHEMBL12972944 | 0.77 | LTA4H (0.39) | LTA4HACHEBCHEFDPS | |
| SCHEMBL29508453 | 0.76 | ROCK2 (0.55) | ACHE | |
| SCHEMBL21345579 | 0.76 | ROCK2 (0.55) | ACHE | |
| SCHEMBL12972910 | 0.75 | ACHE (0.41) | LTA4HACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240501-B1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE | UNIV NANTES (FR) | 2015-10-14 | — | — | EP | disclosed |
| US-8361993-B2 | Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue | UNIVERSITE DE NANTES (FR) | 2013-01-29 | — | — | US | disclosed |
| US-8361993-B2 | Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue | UNIVERSITE DE NANTES (FR) | 2013-01-29 | — | — | US | disclosed |
| US-8361993-B2 | Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue | UNIVERSITE DE NANTES (FR) | 2013-01-29 | — | — | US | disclosed |
| US-20100311695-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR TARGETING BONE TISSUE | UNIVERSITE DE NANTES | 2010-12-09 | — | — | US | disclosed |
| US-20100311695-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR TARGETING BONE TISSUE | UNIVERSITE DE NANTES | 2010-12-09 | — | — | US | disclosed |
| US-20100311695-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR TARGETING BONE TISSUE | UNIVERSITE DE NANTES | 2010-12-09 | — | — | US | disclosed |
| WO-2009083614-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE | UNIVERSITE DE NANTES (FR) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311695-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR TARGETING BONE TISSUE | BPGM, SOST, PTH1R | LTA4H 2236/4885ACHE 4870/4885BCHE 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.