Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883825 | 0.81 | AADAT (0.51) | AADATNOTUMGAATSHRAGTR2 | |
| SCHEMBL27883834 | 0.81 | AADAT (0.51) | AADATNOTUMGAATSHRAGTR2 | |
| SCHEMBL27867457 | 0.81 | UCHL1 (0.37) | AGTR2 | |
| SCHEMBL27867427 | 0.78 | UCHL1 (0.41) | GRM2GRM3AGTR2HTR1A | |
| SCHEMBL27883829 | 0.77 | NOTUM (0.47) | AADATNOTUMGAAAGTR2 | |
| SCHEMBL5563210 | 0.73 | KDM4E (0.47) | AGTR2 | |
| SCHEMBL5563204 | 0.73 | KDM4E (0.47) | AGTR2 | |
| SCHEMBL1445011 | 0.73 | ACE (0.51) | — | |
| SCHEMBL27883864 | 0.70 | LDHA (0.51) | — | |
| SCHEMBL10441493 | 0.69 | NOTUM (0.44) | NOTUMGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |