Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.63 |
| ▸ | DDX3X | O00571 | 11/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291 | 0.88 | LDHA (0.67) | LDHADDX3XNOTUMMAOAMAOB | |
| SCHEMBL8027 | 0.77 | LDHA (1.00) | LDHA | |
| SCHEMBL8317 | 0.77 | LDHA (0.72) | LDHADDX3XMIF | |
| SCHEMBL7734 | 0.75 | LDHA (1.00) | LDHAMAOAMAOB | |
| SCHEMBL27867442 | 0.72 | DDX3X (0.42) | LDHADDX3XP2RX7MIF | |
| SCHEMBL29828549 | 0.69 | MAOA (0.66) | LDHADDX3XP2RX7MIFMAOA | |
| SCHEMBL28309985 | 0.68 | MIF (0.49) | DDX3XP2RX7MIFNOTUMGABRA2 | |
| SCHEMBL8304 | 0.66 | LDHA (0.87) | LDHAMIFNOTUMMAOAMAOB | |
| SCHEMBL8260 | 0.66 | DAO (0.59) | LDHA | |
| SCHEMBL21974268 | 0.65 | RXRA (0.59) | DDX3XMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | UNIVERSITÀ DI PISA (IT) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | LDHA, LDHB, DLD | LDHA 1/4885DDX3X 975/4885P2RX7 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.