Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883834 | 0.81 | AADAT (0.51) | AGTR2 | |
| SCHEMBL27867459 | 0.81 | AADAT (0.51) | AGTR2 | |
| SCHEMBL27883825 | 0.81 | AADAT (0.51) | AGTR2 | |
| SCHEMBL27867427 | 0.78 | UCHL1 (0.41) | UCHL1AGTR2 | |
| SCHEMBL27883829 | 0.77 | NOTUM (0.47) | AGTR2GSK3B | |
| SCHEMBL1445011 | 0.73 | ACE (0.51) | ACE | |
| SCHEMBL9849125 | 0.71 | POLB (0.43) | AGTR2ACE | |
| SCHEMBL16267710 | 0.71 | POLB (0.43) | AGTR2ACE | |
| SCHEMBL27883864 | 0.70 | LDHA (0.51) | — | |
| SCHEMBL27867431 | 0.69 | NOTUM (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |