Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883834 | 0.78 | AADAT (0.51) | AGTR2 | |
| SCHEMBL27867457 | 0.78 | UCHL1 (0.37) | UCHL1AGTR2 | |
| SCHEMBL27883825 | 0.78 | AADAT (0.51) | AGTR2 | |
| SCHEMBL27867459 | 0.78 | AADAT (0.51) | AGTR2HTR1AGRM2GRM3 | |
| SCHEMBL10441493 | 0.76 | NOTUM (0.44) | — | |
| SCHEMBL27883864 | 0.76 | LDHA (0.51) | — | |
| SCHEMBL27883829 | 0.75 | NOTUM (0.47) | AGTR2 | |
| SCHEMBL1445011 | 0.74 | ACE (0.51) | — | |
| SCHEMBL27883831 | 0.72 | XIAP (0.42) | AGTR2 | |
| SCHEMBL27867409 | 0.71 | AGTR2 (0.52) | UCHL1USP30AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |