Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298183 | 0.85 | L3MBTL1 (0.47) | ITGB3ITGA2BALDH1A1L3MBTL1LMNA | |
| SCHEMBL11571244 | 0.85 | CTRC (0.45) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL28101686 | 0.84 | REN (0.38) | ITGB3ITGA2BALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL7362550 | 0.83 | LMNA (0.49) | ITGB3ITGA2BALDH1A1L3MBTL1LMNA | |
| SCHEMBL20166038 | 0.83 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL27644241 | 0.83 | FOLH1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL27644244 | 0.83 | FOLH1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL28365896 | 0.82 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1LMNAHSD17B10CYP3A4 | |
| SCHEMBL7273178 | 0.82 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1LMNAHSD17B10CYP3A4 | |
| SCHEMBL28365893 | 0.82 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1LMNAHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659920-A | C-end phenylalanine p-amino modified endomorphine-1 analog and preparation and application thereof | UNIV LANGZHOU | 2012-09-12 | — | — | CN | disclosed |