Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147368 | 0.83 | DYRK1A (0.40) | DYRK1AGSK3BNFATC1MAPK1ALDH1A1 | |
| Cadaverine Tartrate SCHEMBL27875442 | 0.79 | ALDH1A1 (0.38) | DYRK1AGSK3BNFATC1ALDH1A1ADORA2A | |
| Cadaverine Tartrate SCHEMBL5874237 | 0.71 | ALDH1A1 (0.63) | MAPK10ALDH1A1MAPTNPSR1KDM4E | |
| Cadaverine Tartrate SCHEMBL5874249 | 0.71 | ALDH1A1 (0.63) | MAPK10ALDH1A1MAPTNPSR1KDM4E | |
| Cadaverine Tartrate SCHEMBL28081412 | 0.71 | ALDH1A1 (0.63) | MAPK10ALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL27939095 | 0.69 | SLC22A6 (0.54) | DYRK1AGSK3BNFATC1MAPK1ALDH1A1 | |
| Quinoline SCHEMBL28251318 | 0.67 | ALDH1A1 (0.57) | LRRK2MAPK1ALDH1A1MAPTKDM4E | |
| Quinoline SCHEMBL27950148 | 0.67 | ALDH1A1 (0.49) | DYRK1AGSK3BNFATC1LRRK2MAPK1 | |
| SCHEMBL8664315 | 0.66 | ALDH1A1 (0.51) | MAPK1ALDH1A1MAPTKDM4E | |
| Cadaverine Tartrate SCHEMBL28147371 | 0.65 | KEAP1 (0.47) | SLC22A12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702067-A | Novel intermediate for synthesizing silodosin as well as preparation method and purpose of novel intermediate | BEIJING LIANBEN MEDICAL CHEMICAL TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |