Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 1/20 | 0.41 |
| ▸ | IGF2R | P11717 | 1/20 | 0.40 |
| ▸ | AMY2A | P04746 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884623 | 0.89 | LGALS8 (0.41) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL2787564 | 0.86 | LGALS8 (0.55) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL16460079 | 0.86 | LGALS8 (0.55) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| Cellobiose SCHEMBL5310426 | 0.86 | LGALS8 (0.55) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| SCHEMBL2691427 | 0.86 | IGF2R (0.44) | LGALS8LGALS3LGALS4IGF2R | |
| Cellobiose SCHEMBL11230654 | 0.85 | LGALS8 (0.49) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| SCHEMBL1134654 | 0.85 | IGF2R (0.43) | LGALS8LGALS3LGALS4IGF2RHSD17B10 | |
| SCHEMBL114715 | 0.85 | IGF2R (0.43) | LGALS8LGALS3LGALS4IGF2RAMY2A | |
| SCHEMBL6651759 | 0.85 | IGF2R (0.43) | LGALS8LGALS3LGALS4IGF2RHSD17B10 | |
| Water SCHEMBL21777653 | 0.84 | IGF2R (0.42) | LGALS8LGALS3LGALS4IGF2RHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440241-A | Calcium fortified grape-based products and methods of making same | WELCH FOODS INC (US) | 2003-09-03 | — | — | CN | claimed |
| CN-85105898-A | With the manufacture method that is 2-benzyl-4-(4-pyridine radicals) thiazoles He its derivative of immunomodulator | — | 1987-01-21 | — | — | CN | claimed |
| EP-3966212-A1 | PRODRUG COMPOUNDS | Bristol-Myers Squibb Company (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-107586293-A | Sulfur-bearing dibenzothiazine alkaloid compound and application thereof | 胡梨芳 | 2018-01-16 | — | — | CN | disclosed |
| CN-106749481-A | Enoxolone class noval chemical compound entity and application thereof | 刘力 | 2017-05-31 | — | — | CN | disclosed |
| US-9475759-B2 | Tigecycline crystalline hydrate and preparation method therefor and use thereof | HU LIFANG (CN) | 2016-10-25 | — | — | US | disclosed |
| CN-105837646-A | Flavonoid new chemical entity, composition and use | 刘力 | 2016-08-10 | — | — | CN | disclosed |
| CN-105566316-A | Dibenzo quinolizine compound entity and application thereof | LIU LI | 2016-05-11 | — | — | CN | disclosed |
| CN-105461713-A | New benzonaphthyridine compound, and composition and use thereof | LIU LI | 2016-04-06 | — | — | CN | disclosed |
| CN-105272913-A | Isoquinoline compounds and composition and use thereof | LIU LI | 2016-01-27 | — | — | CN | disclosed |
| CN-103012421-B | Iloquinoline derivative medicine and preparation thereof and purposes | LIU LI (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-1646164-A | Process for the preparation of a nutrient formulation | CHEMSTOP PTY LTD (AU) | 2005-07-27 | — | — | CN | disclosed |
| CN-1440241-A | Calcium fortified grape-based products and methods of making same | WELCH FOODS INC (US) | 2003-09-03 | — | — | CN | disclosed |
| EP-0723537-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS ESTROGEN AGONISTS | PFIZER INC. (US) | 1996-07-31 | — | — | EP | disclosed |
| US-5510119-A | DOSAGE FORM | RECORDATI S.A., CHEMICAL AND PHARMACEUTICL COMPANY (CH) | 1996-04-23 | — | — | US | disclosed |
| US-5405619-A | Controlled release therapeutic system for liquid pharmaceutical formulations | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-04-11 | — | — | US | disclosed |
| US-5296236-A | Coated microgranules | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1994-03-22 | — | — | US | disclosed |
| EP-0584285-A1 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | Snorrason, Ernir (IS) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992020328-A2 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | SNORRASON ERNIR (IS) | 1992-11-26 | — | — | WO | disclosed |
| CN-85107805-A | Manufacture method as N-alkenyl-3-hydroxy benzo [b] the thiophene-2-carboxamide derivatives derivative of dual-purpose cyclooxygenase and lipoxidase inhibitor | — | 1986-12-31 | — | — | CN | disclosed |