Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879638 | 0.79 | LMNA (0.46) | GFERCYP1A2LMNATSHRSMN1; SMN2 | |
| SCHEMBL27896395 | 0.74 | LMNA (0.41) | GFERCYP1A2LMNATSHRSMN1; SMN2 | |
| SCHEMBL27896539 | 0.72 | ALDH1A1 (0.48) | LMNATSHRALDH1A1KDM4ERAB9A | |
| SCHEMBL27879631 | 0.72 | TAS1R3 (0.41) | CYP1A2SMN1; SMN2ALDH1A1CYP2C19KDM4E | |
| SCHEMBL27896422 | 0.71 | TDP1 (0.42) | CYP1A2ALDH1A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL845403 | 0.71 | GFER (0.46) | GFERLMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27879636 | 0.70 | CHRM2 (0.37) | — | |
| SCHEMBL23573453 | 0.69 | SMN1; SMN2 (0.59) | GFERCYP1A2LMNATSHRSMN1; SMN2 | |
| SCHEMBL7408815 | 0.67 | POLB (0.36) | L3MBTL1POLBCYP3A4 | |
| SCHEMBL27896574 | 0.67 | CHRNB2 (0.40) | ALDH1A1GAAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |