Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896395 | 0.82 | LMNA (0.41) | LMNACYP1A2TSHRKDM4ERAB9A | |
| SCHEMBL27879622 | 0.79 | GFER (0.45) | LMNACYP1A2TSHRKDM4ERAB9A | |
| SCHEMBL27879627 | 0.70 | VHL (0.65) | KMT2A | |
| SCHEMBL28054810 | 0.69 | PIK3CD (0.55) | — | |
| SCHEMBL18081195 | 0.65 | LMNA (0.55) | LMNACYP1A2TSHRKDM4ERAB9A | |
| SCHEMBL28799491 | 0.65 | HSD17B10 (0.45) | LMNATSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14731487 | 0.65 | LMNA (0.70) | LMNACYP1A2TSHRKDM4ERAB9A | |
| SCHEMBL27896445 | 0.64 | ATM (0.30) | — | |
| SCHEMBL27879619 | 0.62 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL18081250 | 0.62 | LMNA (0.51) | LMNACYP1A2TSHRKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |