Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781704 | 0.80 | NFKB1 (0.32) | — | |
| SCHEMBL27523363 | 0.74 | P2RX7 (0.39) | P2RX7HSP90AA1 | |
| SCHEMBL5157780 | 0.69 | MLYCD (0.33) | — | |
| Pyrimidine SCHEMBL28193431 | 0.68 | P2RX7 (0.41) | P2RX7 | |
| Pyridine SCHEMBL28193390 | 0.67 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL5264575 | 0.66 | RAB9A (0.39) | — | |
| SCHEMBL28755305 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL9272029 | 0.65 | ALDH1A1 (0.42) | HSP90AA1 | |
| SCHEMBL4919254 | 0.64 | NPSR1 (0.42) | ATM | |
| SCHEMBL4107497 | 0.64 | L3MBTL1 (0.47) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971323-A | Heterocyclic compounds as JANUS kinase inhibitors | BIOCRYST PHARM INC | 2013-03-13 | — | — | CN | disclosed |