Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789762 | 0.88 | ITGB1 (0.31) | — | |
| SCHEMBL2790813 | 0.81 | PROKR1 (0.36) | PROKR1 | |
| SCHEMBL2790320 | 0.79 | KDM4E (0.42) | PROKR1 | |
| SCHEMBL2812730 | 0.78 | PROKR1 (0.39) | PROKR1GRIN2B | |
| SCHEMBL2790508 | 0.75 | FPR2 (0.34) | — | |
| SCHEMBL2814043 | 0.75 | CNR2 (0.34) | — | |
| SCHEMBL2814040 | 0.75 | CNR2 (0.34) | — | |
| SCHEMBL2790483 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL2790479 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL2791941 | 0.74 | ROCK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |