Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 11/20 | 0.47 |
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | RARG | P13631 | 9/20 | 0.47 |
| ▸ | RXRB | P28702 | 9/20 | 0.47 |
| ▸ | RXRG | P48443 | 7/20 | 0.47 |
| ▸ | RARA | P10276 | 6/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418997 | 0.82 | RARB (0.50) | TP53TSHRALDH1A1SMN1; SMN2RXRA | |
| Terephthalic Acid SCHEMBL29170961 | 0.81 | TSHR (0.71) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL246842 | 0.81 | TSHR (0.71) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27613025 | 0.81 | TSHR (0.80) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28261396 | 0.81 | TSHR (0.80) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL448283 | 0.81 | TSHR (0.80) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL7196429 | 0.80 | TSHR (0.55) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27623313 | 0.80 | TSHR (0.55) | TP53TSHRALDH1A1SMN1; SMN2SRD5A2 | |
| Phthalic Acid SCHEMBL11171682 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL29119962 | 0.79 | RXRA (0.49) | TP53TSHRALDH1A1SMN1; SMN2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649339-B2 | Oxygen scavenging compositions, articles containing same, and methods of their use | PLASTIPAK PACKAGING, INC. (US) | 2023-05-16 | — | — | US | claimed |
| EP-3658616-A1 | HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2020-06-03 | — | — | EP | claimed |
| CN-108473754-A | Polymer resin composition for metal adhesion, metal-resin composite using the same, and electronic product | SK化学株式会社 | 2018-08-31 | — | — | CN | claimed |
| EP-2844692-A1 | OXYGEN SCAVENGING COMPOSITIONS | Plastipak Packaging, Inc. (US) | 2015-03-11 | — | — | EP | claimed |
| US-20140361218-A1 | Oxygen Scavenging Compositions, Articles Containing Same, and Methods of Their Use | PLASTIPAK PACKAGING, INC. (US) | 2014-12-11 | — | — | US | claimed |
| WO-2013165971-A1 | OXYGEN SCAVENGING COMPOSITIONS | CONSTAR INTERNATIONAL LLC (US) | 2013-11-07 | — | — | WO | claimed |
| US-20130285277-A1 | Oxygen Scavenging Compositions, Articles Containing Same, and Methods of Their Use | WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT | 2013-10-31 | — | — | US | claimed |
| EP-1824920-B9 | POLYESTER BASED COBALT CONCENTRATES FOR OXYGEN SCAVENGING COMPOSITIONS | EASTMAN CHEM CO (US) | 2010-08-04 | — | — | EP | claimed |
| EP-1824920-B1 | POLYESTER BASED COBALT CONCENTRATES FOR OXYGEN SCAVENGING COMPOSITIONS | EASTMAN CHEM CO (US) | 2009-09-16 | — | — | EP | claimed |
| EP-1824920-A4 | POLYESTER BASED COBALT CONCENTRATES FOR OXYGEN SCAVENGING COMPOSITIONS | EASTMAN CHEM CO (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1824920-A2 | POLYESTER BASED COBALT CONCENTRATES FOR OXYGEN SCAVENGING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2007-08-29 | — | — | EP | claimed |
| EP-1086978-B1 | ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME | TAKIRON CO (JP) | 2007-04-11 | — | — | EP | claimed |
| WO-2006062816-A2 | POLYESTER BASED COBALT CONCENTRATES FOR OXYGEN SCAVENGING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2006-06-15 | — | — | WO | claimed |
| US-20060128861-A1 | Polyester based cobalt concentrates for oxygen scavenging compositions | EASTMAN CHEMICAL COMPANY | 2006-06-15 | — | — | US | claimed |
| US-6569531-B1 | Adding multifunctional additive to thermoplastic polyester resin, allowing to react with molecules of resin which is in molten state, molding to produce additive-containing resin molded article | TAKIRON CO., LTD. (JP) | 2003-05-27 | — | — | US | claimed |
| EP-1086978-A1 | ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME | Takiron Co., Ltd. (JP) | 2001-03-28 | — | — | EP | claimed |
| CN-115678267-B | High-reflection white LED nylon bracket material | 浙江普利特新材料有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4236717-A1 | POLYOLEFIN-BASED RESINS, SOLE STRUCTURES, AND ARTICLES OF FOOTWEAR AND SPORTING EQUIPMENT FORMED THEREFROM | Nike Innovate C.V. (US) | 2023-09-06 | — | — | EP | disclosed |
| US-4525404-A | Pile articles with attenuated upper portion and a method for producing the same | KANEBO, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0134141-A2 | Pile articles and their production | KANEBO, LTD. (JP) | 1985-03-13 | — | — | EP | disclosed |